Introduction

Classification criteria

Prevalence

Clinical features

Fibromyalgia assessment

Fibromyalgia subgroups

Controversy over classification criteria

Differential diagnosis

Pathophysiological mechanisms

Abnormalities in sensory processing

Neurotransmitters

Cytokines

Hypothalamo-pituitary-adrenal axis

Autonomic nervous system

Psychological, cognitive and behavioral factors

Genetic predisposition

External stressors

Management

Nonpharmacological management

Pharmacologic treatment

Conclusion