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CLINICAL DEFINITION
EPIDEMIOLOGY
MANAGEMENT
PATHOPHYSIOLOGY OF CHRONIC FATIGUE SYNDROME
Viral/Immune Hypotheses
Neuropsychiatric Hypotheses
Neuroendocrine Hypotheses
CHRONIC FATIGUE SYNDROME AS A DISORDER OF THE STRESS SYSTEMs
The Stress System
Stress System abnormalities in Chronic Fatigue Disorders
Corticosteroid-Binding Globulin abnormalities and Chronic Fatigue
Pituitary-adrenal hormone abnormalities in chronic fatigue syndrome
CONCLUSION