Table of Contents

1. INTRODUCTION

1.1. CENTRAL CRH AND THE HPA AXIS. PERIPHERAL CRH

1.2.CRH RECEPTORS

2.THE IMMUNE/INFLAMMATORY RESPONSE

3.CRH AND THE IMMUNE/INFLAMMATORY RESPONSE

3.1.CENTRAL CRH AND THE IMMUNE/INFLAMMATORY RESPONSE

3.2.PERIPHERAL CRH AND THE IMMUNE/INFLAMMATORY RESPONSE

3.3.CRH IN THE FEMALE REPRODUCTIVE SYSTEM

4.CRH RECEPTOR ANTAGONISTS. PERSPECTIVES