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	REGULATION OF PLASMA GLUCOSE BY INSULIN
	INSULIN BIOGENESIS AND MECHANISM OF RELEASE
	BIOCHEMISTRY AND ELECTROPHYSIOLOGY OF INSULIN SECRETION
	INSULIN STRUCTURE
	The Insulin Monomer
	The Insulin Dimer
	The Insulin Hexamer
	INSULIN STRUCTURE-FUNCTION RELATIONSHIPS
	A-Chain Analysis
	CRITICAL ANALYSIS OF INSULIN B-CHAIN DOMAINS
	Importance of the B-Chain NH2-terminus
	Importance of the B-Chain COOH-terminus
	Specific Importance of PheB24
	Specific Importance of PheB25