HORMONAL REGULATION OF BREAST DEVELOPMENT

The initiation and progression of breast development involves a coordinated effort of pituitary and ovarian hormones, as well as local mediators (Figure 1).

Figure 1. Hormones affecting growth and differentiation of breast tissue. (GH= Growth Hormone; ER= Estrogen Receptor; PR= Progesterone Receptor; AR= Androgen Receptor; PROLR= Prolactin Receptor)

Hormones affecting growth and differentiation of breast tissue. (GH= Growth Hormone; ER= Estrogen Receptor; PR= Progesterone Receptor; AR= Androgen Receptor; PROLR= Prolactin Receptor)