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	1. INTRODUCTION
	2. TESTOSTERONE PHYSIOLOGY
	2.1 Biosynthesis
	2.2 Secretion
	2.3 Transport
	2.4 Measurement
	2.5 Metabolism
	2.6 Regulation
	2.7 Action
	3. ANDROGEN RECEPTOR
	3.1 Androgen insensitivity
	4. PHARMACOLOGY OF ANDROGENS
	4.1 Indications for Androgen Therapy
	4.1.1 Androgen Replacement Therapy
	4.1.2 Pharmacologic Androgen Therapy
	4.2 Androgen Misuse and Abuse
	4.3 Practical Goals of Androgen Replacement Therapy
	4.4 Pharmacologic Features of Androgens
	4.5 Formulation, Route, and Dose
	4.6 Unmodified Testosterone
	4.6.1 Testosterone Implants
	4.6.2 Transdermal Testosterone
	4.6.3 Testosterone Microspheres
	4.4.6 Oral Testosterone
	4.7 Testosterone Esters
	4.7.1 Injectable
	4.7.2 Oral Testosterone Undecanoate
	4.8 Synthetic Androgens
	4.9 Nonsteroidal Androgens
	4.10 Choice of Preparation
	4.11 Side Effects of Androgen Therapy
	4.12 Monitoring of Androgen Replacement Therapy
	4.13 Contraindications and Precautions for Androgen Replacement Therapy