1. Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N EngJ Med 332:621-628, 1995.
2. Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science 283:212-214, 1999.
3. Rolls ET. The orbitofrontal cortex. Phil Trans R Soc Lond B Biol Sci 351:1433-44, 1996.
4. Karhunen LH, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. Regional cerebral blood flow during food exposure in obese and normal-weight women. Brain 120:1675-84, 1997.
5. Mattes RD. Physiologic responses to sensory stimulation by food: Nutritional implications. J Am Diet Assoc 97:406-410,413; 1997.
6. Berthoud H-R, Kelly L, Zheng H, Patterson LM. Gut and brain interactions in the control of food intake and energy metabolism: Neural pathways of postingestive satiety signals. In: Nutrition, Genetics and Obesity. Bray GA, Ryan DH, eds., Baton Rouge, Louisiana State Univ. Press, 1999, pp 208-226.
7. Havel PJ. Peripheral signals conveying metabolic information to the brain: Short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med 226:963-77, 2001.
8. Rolls BJ, Castellanos VH, Halford JC, Kilara A, Panyam D, Pelkman CL, Smith GP, Thorwart ML. Volume of food consumed affects satiety in men. Am J Clin Nutr 67:1170-1177, 1998.
9. Blundell JE, Stubbs RJ. Diet composition and th control of food intake in humans. In: Bray GA, Bouchard C, James WPT, eds. Handbook of Obesity, Marcel Dekker, Inc., New York, 1998, pp 243-272.
10. Geliebter A. Gastric distension and gastric capacity in relation to food intake in humans. Physiol Behav 44:665-8, 1988.
11. Kim DY, Camilleri M, Murray JA, Stephens DA, Levine JA, Burton DD. Is there a role for gastric accommodation and satiety in asymptomatic obese people? Obes Res 9:655-61, 2001.
12. Karlsson J, Sjostrom L, Sullivan M. Swedish obese subjects (SOS)--an intervention study of obesity. Two-year follow-up of health-related quality of life (HRQL) and eating behavior after gastric surgery for severe obesity. Int J Obes Relat Metab Disord 22:113-26, 1998.
13. Ladabaum U, Minoshima S, Hasler WL, Cross D, Chey WD, Owyang C. Gastric distention correlates with activation of multiple cortical and subcortical regions. Gastroenterology 120:369-76, 2001.
14. Verdich C, Madsen JL, Toubro S, Buemann B, Holst JJ, Astrup A. Effect of obesity and major weight reduction on gastric emptying. Int J Obes Relat Metab Disord 24:899-905, 2000.
15. Moran TH. Cholecystokinin and satiety: current perspectives. Nutrition 16:858-65, 2000.
16. Ghijsen WEJM, Leenders AGM, Wiegant VM. Regulation of cholecystokinin release from central nerve terminals. Peptides 22:1213-1221, 2001.
17. Leibowitz SF, Hoebel BG. Behavioral neuroscience of obesity. In: Bray GA, Bouchard C, James WPT, eds. Handbook of Obesity, Marcel Dekker, Inc., New York, 1998, pp 313-358.
18. Drucker DJ. Biological actions and therapeutic potential of the glucagon-like peptides. Gastroenterology. 122:531-544, 2002.
19. Edwards CM, Stanley SA, Davis R, Brynes AE, Frost GS, Seal LJ, Ghatei MA,
Bloom SR. Exendin-4 reduces fasting and postprandial glucose and decreases
energy intake in healthy volunteers. Am J Physiol Endocrinol Metab
281:E155-E161, 2001.
20. Horvath TL, Diano S, Sotonyi P, Heiman M, Tschop M. Minireview: Ghrelin and the regulation of energy balance- A hypothalamic perspective. Endocrinol 142:4163-4169, 2001.
21. Tso P, Liu M, Kalogeris TJ, Thomson ABR. The role of apolipoprotein A-IV in the regulation of food intake. Ann Rev Nutr 21:231-254, 2001.
22. Lui M, Doi T, Shen L, Woods SC, Seeley RJ, Zheng S, Jackman A, Tso P. Intestinal satiety protein apolipoprotein AIV is synthesized and regulated in rat hypothalamus. Am J Physiol 280:R1382-R1387; 2001.
23. Lui M, Shen L, Tso P. The role of enterstatin and apolipoprotein AIV on the control of food intake. Neuropeptides 33:425-433, 1999.
24. Rossner S, Barkeling B, Erlanson-Albertsson C, Larsson P, Wahlin-Boll E.
Intravenous enterostatin does not affect single meal food intake in man.
Appetite 24:37-42, 1995.
25. Merali Z, McIntosh J, Anisman H. Role of bombesin-related peptides in the control of food intake. Neuropeptides 33:376-386, 1999.
26. Bray GA. Afferent signals regulating food intake. Proc Nutr Soc 59:373-384, 2000.
27. Woods SC, Seeley RJ. Adiposity signals and the control of energy homeostasis. Nutr 16:894-902, 2000.
28. Schwartz MW, Woods SC, Porte D, Jr, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature 404:661-671, 2000.
29. Geary N. Effects of glucagon, insulin, amylin and CGRP on feeding. Neuropeptides 33:400-405, 1999.
30. Reidelberger RD, Arnelo U, Granqvist L, Permert J. Comparitive effects of amylin and cholecystokinin on food intake and gastric emptying in rats. Am J Physiol 280:R605-R611, 2001.
31. Friedman JM. Leptin, leptin receptors, and the control of body weight. Nutr Rev 56:S38-S46, 1998.
32. Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393:684-8, 1998.
33. Holness MJ, Munns MJ, Sugden MC. Current concepts concerning the role of leptin in reproductive function. Mol Cell Endocrinol. 157:11-20, 1999.
34. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, et al. Serum immunoreactive-leptin concentrations in normal weight and obese humans. N Eng J Med 334:292-295, 1996.
35. Rosenbaum M, Leibel RL. Role of gonadal steroids in the sexual dimorphisms in body composition and circulating concentrations of leptin. J Clin Endocrinol Metab 84:1784-1789, 1999.
36. Considine RV, Caro JF. Leptin and the regulation of body weight. Int J Biochem Cell Biol 29:1255-1272, 1997.
37. Kolaczynski JW, Considine RV, Ohannesian J, Marco C, Opentanova I, Nyce MR, Myint M, Caro JF. Responses of leptin to short-term fasting and refeeding in humans: A link with ketogenesis but not ketones themselves. Diabetes 45:1511-1515, 1996.
38. Considine RV, Cooksey RC, Williams LB, Fawcett RL, Zhang P, Ambrosius WT, Whitfield RM, Jones RM, Inman M, Huse J, McClain DA. Hexosamines regulate leptin production in human subcutaneous adipocytes. J Clin Endo Metab 85:3551-3556, 2000.
39. Flier JS. What's in a name? In search of leptin's physiologic role. J Clin Endocrinol Metab 83:1407-1413, 1998.
40. Tartaglia LA. The leptin receptor. J Biol Chem 272:6093-6096, 1997.
41. Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes IA, McCamish MA, O'Rahilly S. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. NEJM 341:879-884, 1999.
42. Heymsfield SB, Greenberg AS, Fujioka K, Dixon RM, Kusher R, Hunt T, Lubina JA, Patane J, Self B, Hunt P, McCamish M. Recombinant leptin for weight Loss in obese and lean adults. JAMA 282:1568-1575, 1999.
43. Hukshorn CJ, Saris WHM, Westerterp-Plantenga S, Farid AR, Smith FJ, Campfield LA. Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men. J Clin Endocrinol Metab 85:4003-4009, 2000.
44. Cavagnini F, Croci M, Putignano P, Petroni ML, Invitti C. Glucocorticoids and neuroendocrine function. Int J Obesity 24 Suppl 2:S77-S79, 2000.
45. Seckl JR, Walker BR. Minireview: 11?-hydroxysteroid dehydrogenase type 1- A tissue-specific amplifier of glucocorticoid action. Endocrinol 142:1371-1376, 2001.
46. Plata-Salaman CR. Cytokines and feeding. Int J Obesity 25 Suppl 5:S48-S52, 2001.
47. Fawcett RL, Waechter AS, Williams LB, Zhang P, Louie R, Jones RM, Inman M, Huse J, Considine RV. TNF? inhibits leptin production in subcutaneous and omental adipocytesfrom morbidly obese humans. J Clin Endo Metab 85:530-535, 2000.
48. Hotamisligil GS. Molecular mechanisms of insulin resistance and the role of the adipocyte.Int J Obesity 24 Suppl 4:S23-S27, 2000.
49. Bray GA Static theories in a dynamic world: a glucodynamic theory of food
intake.
Obes Res 4:489-492, 1996.
50. Louis-Sylvestre J, Le Magnen J. Fall in blood glucose level precedes meal onset in free-feeding rats. Neurosci Biobehav Rev. 4 Suppl 1:13-15,1980.
51. Campfield LA, Smith FJ, Rosenbaum M, Hirsch J. Human eating: evidence for a physiological basis using a modified paradigm. Neurosci Biobehav Rev. 20:133-137, 1996.
52. Liu XH, Morris R, Spiller D, White M, Williams G. Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro. Diabetes 50:2431-2437, 2001.
53. DiMeglio DP, Mattes RD. Liquid versus solid carbohydrate: effects on food intake and body weight. Int J Obes Relat Metab Disord. 24:794-800, 2000.
54. Mattes RD, Rothacker D. Beverage viscosity is inversely related to postprandial hunger in humans. Physiol Behav. 74:551-557, 2001.
55. Rolls BJ. The role of energy density in the overconsumption of fat. J Nutr. 130:268S-271S, 2000.