Hypocalcemia: Diagnosis and Treatment - Chapter 7 : DISEASES OF BONE AND MINERAL METABOLISM - Table of Contents | EndoText.org

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CLINICAL PRESENTATION OF HYPOCALCEMIA
ETIOLOGY OF HYPOCALCEMIA
Hypocalcemia can result from disorders of vitamin D metabolism and action, hypoparathyroidism, resistance to parathyroid hormone (PTH), or a number of other conditions (Table 2). These topics are discussed in separate sections below.
VITAMIN D DISORDERS RESULTING IN HYPOCALCEMIA
Inherited Disorders of Vitamin D Metabolism and Action
Nutritional Vitamin D Deficiency
HYPOPARATHYROIDISM
Post-Surgical Hypoparathyroidism and Hypocalcemia
Developmental Disorders of the Parathyroid Gland
Genetic Etiologies of Hypoparathyroidism
Hypoparathyroidism in Association with Syndromes
Familial Isolated Hypoparathyroidism
Mutations Affecting the Extracellular Calcium-Sensing Receptor
Hypoparathyroidism, Sensory Neural Deafness, Renal Dysplasia Syndrome
Polyglandular Autoimmune Disease
PSEUDOHYPOPARATHYROIDISM
Pathophysiology
Signs and Symptoms
Diagnosis and Management of Pseudohypoparathyroidism
Pseudopseudohypoparathyroidism
OTHER CAUSES OF HYPOCALCEMIA
Neonatal Hypocalcemia
Factitious Hypocalcemia Due to Hypoalbuminemia or to Gadolinium Administration
Hypomagnesemia
Hyperphosphatemia
Medications and Toxins
"Hungry Bone Syndrome"
Pancreatitis
Hypocalcemia Associated With Critical Illness
Transfusion-Related Causes of Hypocalcemia
TREATMENT OF HYPOCALCEMIA
The decision to treat is dependent on presenting symptoms, and the severity and rapidity with which hypocalcemia develops.
Acute Hypocalcemia
Chronic Hypocalcemia
Replacement with PTH for Hypoparathyroidism