Question 2

Based on the rapid progression and severity of symptoms, you are concerned for a more sinister cause. Which of the following laboratory tests is most likely to differentiate between an adrenal or ovarian source of excess androgens?


17-OH progesterone is normal in this patient and does not contribute to hyperandrogenism. Adrenal and ovarian tumors cause hirsutism because of elevated levels of adrenal androgens (androstenedione, DHEA, DHEA-S) and testosterone.

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