Figure 6: Metabolism of adrenal androgens in the pilosebaceous unit (A) and adipocyte tissue (B). Abbreviations: A, Δ4-androstenedione; T, testosterone; DHT, dihydrotestosterone; R, receptor; 3β-HSD, 3β-hydroxysteroid dehydrogenase; 17β-HSD, 17β-hydroxysteroid dehydrogenase; 5α-r, 5α-reductase; 3α-, 3β -diol, 3α-androstenediol, 3β-androstenediol; 3α-, 3β- diol-G, 3α-diol-glucuronide, 3β-diol-glucuronide; androsterone-G, androsterone glucuronide; ar, aromatase; E1, estrone; E2, 17β-estradiol