Figure 7. Diagnostic and therapeutic approach to the patient with an incidentally detected adrenal mass, according to the NIH state-of-the-science conference statement . We recommend an endocrinologic reevaluation after 2 years in patients with a tumor size > 3 cm . PAC: plasma aldosterone concentration; PRC: Plasma Renin Concentration. APA: Aldosterone producing adenoma. SCCS: Subclinical Cushing Syndrom. ?: in addition to biochemical results, clinical signs of possible hypercortisolims (e. g. weight gain, arterial hypertension etc.) have to evaluated carefully, before surgery can be recommended.