Figure 2. Health Conditions Associated With Increased Risk of CVD (97). †Any moderate-risk condition with ≥2 additional risk enhancers. ‡Severe obesity is defined as BMI ≥99th percentile or ≥35 kg/m2, and obesity is defined as BMI ≥95th percentile to <99th percentile. §Defined as blood pressure >95th percentile or ≥130/80 mmHg on 3 separate occasions. ΔDefined as ≥3 risk enhancers. ‖ Involves obstructive lesions of the left ventricle and aorta, cyanotic congenital heart defects leading to Eisenmenger syndrome, and congenital coronary artery anomalies in isolation or in association with other congenital defects. ApoB, apolipoprotein B; BMI, body mass index; CKD, chronic kidney disease; CVD, cardiovascular disease; DM, diabetes mellitus; ESRD, end-stage renal disease; FH, familial hypercholesterolemia; HeFH, heterozygous familial hypercholesterolemia; HIV, human immunodeficiency virus; HoFH, homozygous familial hypercholesterolemia; Lp(a), lipoprotein (a); MI, myocardial infarction.