Figure 4. Microheterogeneity of TBG. Tracer amounts of l25I T4 were added to serum prior to submission to isoelectric focusing and radioautography. TBG C (common type) exhibits 6 bands spanning from pH 4.18 to 4.58. Three of the six are major and shown here between pH 4.35 and 4.50. TBG-Slow (TBG S) from a hemizygous male shows a cathodally shifted pattern. A mixed pattern occurs in heterozygous females expressing both TBG-C and TBG-S. [Reproduced from Waltz et al (56)].