Figure 7. (a) Corticotrophs are round basophilic cells that are readily identified on H&E-stained sections. (b) They are concentrated mainly in the central region of the gland known as the “mucoid wedge” and are the main components of the vestigial intermediate lobe that is composed of small cysts (C). (c) They have characteristic “enigmatic bodies”, large cytoplasmic vacuoles that represent complex lysosomes (arrows).