etx-lipidspeds-ch-35-fig1

Figure 1. Phenotypic variability in familial hypercholesterolemia. LDL, low-density lipoprotein; APOB, apolipoprotein B; PCSK9, pro-protein convertase subtilisin/kexin type 9; LDLRAP1, LDL receptor adaptor protein 1 (i.e. ARH, autosomal recessive hypercholesterolaemia). (Adapted from Cuchel, M., et al., Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Eur Heart J, 2014. 35(32): p. 2146-57)

Figure 1. Phenotypic variability in familial hypercholesterolemia. LDL, low-density lipoprotein; APOB, apolipoprotein B; PCSK9, pro-protein convertase subtilisin/kexin type 9; LDLRAP1, LDL receptor adaptor protein 1 (i.e. ARH, autosomal recessive hypercholesterolaemia). (Adapted from Cuchel, M., et al., Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Eur Heart J, 2014. 35(32): p. 2146-57)

Figure 1. Phenotypic variability in familial hypercholesterolemia. LDL, low-density lipoprotein; APOB, apolipoprotein B; PCSK9, pro-protein convertase subtilisin/kexin type 9; LDLRAP1, LDL receptor adaptor protein 1 (i.e. ARH, autosomal recessive hypercholesterolaemia). (Adapted from Cuchel, M., et al., Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Eur Heart J, 2014. 35(32): p. 2146-57)