GR Figure 8

Figure 8: Intracellular circulation of GR.
Circulation of GR between the cytoplasm and the nucleus, and its transcriptional regulation on the glucocorticoid-responsive genes in the nucleus are shown in the panel. GR translocates into mitochondria or lysosomes as well.
GREs: glucocorticoid responsive elements; TFREs: transcription factor responsive elements; HSPs: heat shock proteins; TF: transcription factor
From (59).