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Figure 4. Two-cell, two-gonadotropin hypothesis of regulation of estrogen synthesis in the human ovary. Adapted by Carr, BR. Diseases of the ovary and Reproductive Tract. In Wilson JD, Foster DW, Kronenberg HM, Larsen PR, eds. Williams Textbook of Endocrinology 9th edition. WB Saunders, Philadelphia, p.751-817.