figure9

Figure 10: Three different modes of transcriptional regulation of the glucocorticoid-responsive promoters by GR.

GR may interact with other transcription factors directly or indirectly. A protein or a protein complex may intermediate their association in the latter case.

GR: glucocorticoid receptor; GREs: glucocorticoid responsive elements; TF: transcription factor; TFREs: transcription factor responsive elements