figure6

Figure 6:Metabolism of adrenal androgens in the pilosebaceous unit (A) and adipocyte tissue (B).Abbreviations: A, 4-androstenedione; T, testosterone; DHT, dihydrotestosterone; R, receptor; 3-HSD, 3-hydroxysteroid dehydrogenase; 17-HSD, 17hydroxysteroid dehydrogenase; 5-r, 5-reductase; 3a-, 3-diol, 3-androstenediol, 3-androstenediol; 3a-, 3-diol-G, 3-diol-glucuronide, 3-diol-glucuronide; androsterone-G, androsterone glucorunide; ar, aromatase; E1, estrone; E2, estradiol-17.