Figure 12:Plasma corticosterone circadian rhythms in normal rats (open symbols, dashed line) and in a diabetic rat under mild stress (solid symbols, solid line). There is not a significant increase in mean daily levels of corticosterone in the diabetic rat. However, during the period of inactivity, the circadian nadir does not occur. Reprinted by permission from Macmillan Publishers Ltd: International Journal of Obesity, ref (83) , copyright 2000.